Dr. Maude David, Assistant Professor
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Office | 534 Nash Hall | Academic Bio |
Phone | 541-737-0629 | ||
FAX | 541-737-0496 | Laboratory Website davidlab.science.oregonstate.edu |
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maude.david@oregonstate.edu | |||
Education | Ph.D. Ecole Centrale de Lyon, U. of Lyon, France |
Research Interests: Computational Biology; Microbial Ecology; Gut-Brain Axis
Courses Taught: MB 599: Capstone Problem-Solving Course in Biological Data Sciences; BSD 491/492: Capstone Projects in Biological Data Science I and II
RESEARCH
Dr. Maude David's laboratory studies the gut-brain axis, to understand how microbes can impact our behavior, specifically in Autism Spectrum Disorder and Anxiety. She uses a crowd-sourced approach to collect lifestyle type information, diet habits, and samples. Her team is also working on identifying bottlenecks in microbial ecology and bioinformatics, bringing novel solutions to unravel microbial molecular mechanisms by optimizing new molecular methods and improving massive sequencing data annotation.
PRESS RELEASES
https://today.oregonstate.edu/news/osu-part-194-million-grant-study-connection-between-autism-microbiome
KQED: Researchers Hunt for a Link Between Microbiome and Autism by Danielle Venton
CEHG: Cross-referencing analysis of autism to identify novel genes and pathways by Pleuni Pennings
SELECTED PUBLICATIONS
Tataru, C. and David, M.M. 2020. Decoding the language of microbiomes using word-embedding techniques, and applications in inflammatory bowel disease. PLoS Computational Biology 16(5):e1007859.
David, M.M., Tataru, C., Daniels, J., Schwartz, J., Keating, J., Hampton-Marcell, J., Gottel, N., Gilbert, J.A. and Wall, D.P. 2018. Crowdsourced study of children with autism and their typically developing siblings identifies differences in taxonomic and predicted function for stool-associated microbes. bioRxiv:319236.
Kimbrel, J.A., Ballor, N., Wu, Y.W., David, M.M., Hazen, T.C., Simmons, B.A., Singer, S.W. and Jansson, J.K. 2018. Microbial Community Structure and Functional Potential Along a Hypersaline Gradient. Front Microbiol. 9:1492.
Diaz-Beltran, L., Esteban, F.J., Varma, M., Ortuzk, A., David, M. and Wall, D.P. 2017. Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes. BMC Genomics 19(1):315.
David, M.M., Enard, D., Ozturk, A., Daniels, J., Jung, J.Y., Diaz-Beltran, L., and D.P. Wall. 2016. Comorbid analysis of genes associated with autism spectrum disorders reveals differential evolutionary constraints. 2016. PloS ONE 11(7)e0157937.
Hultman, J., Waldrop, M.P., Mackelprang, R., David, M., McFarland, J., Blazewicz, S.J., Harden, J., Turetsky, M.R., McGuire, A.D., Shah, M.B., VerBerkmoes, N.C., Lee, L.H., Mavrommatis, K., and Jansson, J.K. 2015. Multi-omics of permafrost, active layer and thermokarst bog soil microbiomes. Nature 521(7551):208-212.
Sochat, V., David, M., and Wall, D.P. 2015. Translational meta-analytical methods to localize the regulatory patterns of neurological disorders in the human brain. AMIA Ann. Symp. Proc. 2015, 2073.
David, M.M., Cecillon, S., Warne, B., Prestat, E., Jansson, J.K., and Vogel, T.M. 2015. Microbial ecology of chlorinated solvent biodegradation. Environ. Microbiol. 17(12):4835-4850.
Prestat, E., David, M.M., Hultman, J., Tas, N., Lamendella, R., Dvornik, J., Mackelprang, R., Myrold, D.D., Jumpponen, A., Tringe, S.G., Holman, E., Mavromatis, K. and Jansson, J.K. 2014. FOAM (Functional Ontology Assignments for Metagenomes): A hidden Markov Model (HMM) database with environmental focus. Nucleic Acids Res. 42(10):e145-e145.
Bravo, D., Martin, G., David, M.M., Cailleau, G., Verrecchia, E. and Junier, P. 2013. Identification of active oxalotrophic bacteria by Bromodeoxyuridine DNA labeling in a microcosm soil experiment. FEMS Microbiol. Letts. 348(2):103-111.
Nicora, C.D., Anderson, B.J., Callister, S.J., Norbeck, A.D., Purvine, S.O., Jansson, J.K., Mason, O.U., David, M., Jurelevicius, D., Smith, R.D. and Lipton, M.S. 2013. Amino acid treatment enhances protein recovery from sediment and soils for metaproteomic studies. Proteomics 13(18-19):2776-2785.
Mackelprang, R., Waldrop, M.P., DeAngelis, K.M., David, M.M., Chavarria, K.L., Blazewicz, S.J., Rubin, E.M., and Jansson, J.K. 2011. Metagenomic analysis of a permafrost microbial community reveals a rapid response to thaw. Nature 480 (7377):368-371.